WebSep 25, 2024 · Assignee: Incyte Corporation Inventors: Liangxing Wu, Bo Shen, Meizhong Xu, Wenqing Yao Pyrazolopyrimidine compounds and uses thereof Patent number: 11542265 Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. WebMar 29, 2024 · At Incyte, we believe in the power of research to advance scientific innovation and improve patient health. Thanks to the ongoing dedication of the people who …
A patent review of anticancer CDK2 inhibitors (2024–present)
WebIncyteCARES is helping eligible patients during treatment. Find a patient assistance program for eligible patients taking Incyte medication. WebFeb 8, 2024 · PF-07104091 CDK2 Inhibitor Breast Cancer Metastatic Phase 1 New Molecular Entity PF-07248144 KAT6A Epigenetic modifier Breast Cancer Metastatic Phase 1 New Molecular Entity PF-07284890 BRAF BP kinase Inhibitor Melanoma Phase 1 New Molecular Entity PF-07284892 SHP2 tyrosine phosphatase Inhibitor Cancer Phase 1 New Molecular … ipsy dry shampoo
New Drugs on the Horizon sessions offer first disclosures of novel …
WebFeb 26, 2024 · Preclinical research has suggested potential mechanisms of resistance to CDK4/6 inhibitors, including bypass activation of CDK2, 12 with high cyclin E1 (CCNE1) expression correlated with palbociclib resistance in cell line models of breast and ovarian cancer. 13,14 Other studies have shown that CDK6 amplification is associated with … WebFeb 7, 2024 · INCB81776 (AXL/MER), INCB106385 (A2A/A2B), INCB123667 (CDK2) ... Incyte will hold a conference call and webcast this morning at 8:00 a.m. ET. To access the conference call, please dial 877-407-3042 for domestic callers or 201-389-0864 for international callers. When prompted, provide the conference identification number, … WebNov 10, 2024 · Nov. 10, 2024 Researchers from Incyte Research Institute presented the discovery of a cyclin-dependent kinase 2 (CDK2) inhibitor, INCB-123667, being developed for the treatment of cyclin E dysregulated cancers. BioWorld Science Conferences Cancer ipsy email format