Cl4-tcr
WebJun 16, 2008 · A total of 3.5–5 × 10 5 splenocytes from CL4-TCR transgenic mice were injected intravenously into naive VILLIN-HA recipients on day 0. Mice were injected again with 1 × 10 7 splenocytes on days 12 and 27 … WebDownload scientific diagram Tumor growth in the class I-restricted CL4 TCR transgenic mice is not due to tolerization of T cells. In A, 8 10 6 T cells from CL4 mice that developed AB1-HA LO ...
Cl4-tcr
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WebJul 4, 2013 · (A) The cross-presenting capacity of DCs after CpG administration was assessed by measuring the proliferation of CL4 TCR transgenic HA-specific CD8 + T cells. BALB/c mice treated with saline (control) or 20 nmol CpG (CpG) received CFSE-labeled leukocytes from CL4 transgenic mice. Cell-associated HA was administered 18 hours later. WebOct 15, 2014 · Clone 4 (CL4) TCR-transgenic mice, which express a TCR specific for the H-2 d-restricted peptide IYSTVASSL (residues 518–526) of A/PR/8/34 (H1N1) influenza virus HA, were generated and screened as previously described 5, 41. Animal experiments were conducted according to The University of Western Australia Animal Ethics Committee …
WebAug 1, 2006 · Section snippets Mice. VILLIN-HA mice as described 7 express the A/PR8/34 HA from influenza virus A under control of the enterocyte-specific villin promoter. CL4 … Web005308 B10.Cg- H2 d Tg(TcraCl4,TcrbCl4)1Shrm/ShrmJ These transgenic mice express a T-cell receptor specific for an epitope of hemagglutinin that is restricted by MHC class I …
WebNov 15, 2004 · BALB/c mice were inoculated with AB1-HA tumor cells on day 0, then treated with anti-CD40 mAb or PBS on days 14, 16, and 19. On day 21, 1 × 10 7 CFSE-labeled, naive CD8 + CL4-TCR transgenic T cells were adoptively transferred into tumor-bearing recipients and DLN cells were harvested 3 days later and stained for CD8 in conjunction … WebCL4-TCR transgenic CD8(+) T cells were also adoptively transferred into Alb-HA mice. We investigated immunologic mechanisms of CD8(+) T cell-induced liver damage and of …
WebJan 31, 2008 · (referred to as GFAP-HA hereafter). HA peptides are expressed by EGCs and recognized by CD8 T cells that express a T-cell receptor (TCR) specific for K d:HA …
WebApr 13, 2024 · 验证数据. Claudin 4 —— 高生物活性经抗体结合验证. Immobilized Human Claudin-4 Full Length Protein (VLP) (Cat. No. CL4-H52P5) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human Claudin 4 antibody, Human IgG1 with a linear range of 1-63 ng/mL (QC tested). crystal mark documentsWebOct 15, 2012 · Compared with controls, the GFAP-HA × CL4-TCR mice exhibited a selective EGC depletion (34% and 72%) and apoptosis (4% and 14.5%) in the myenteric and submucosal plexus, respectively. These EGC abnormalities were associated with massive intestinal inflammation involving CD8 + T cell-mediated cytotoxic autoimmunity. This … crystal mark download windows 10http://img1.bioon.com/sub/showarticle.asp?sub_id=0&newsid=112634 dwts perfect 10Webby naïve CL4 CD8+ T cells To investigate the role of CD8+ T cells in anti-tumour immunity, our lab utilized CL4 TcR transgenic mice in which virtually all the CD8 + T cells express the Vα10/Vβ8.2 TcR transgene13. These CL4 T cells are able to recognize the dominant Kd-restricted epitope of the Influenza virus A/PR/8 haemagglutinin (HA ... dwts past hostsWebMar 1, 1999 · The CL4 line is restricted by H-2K d and recognizes residues PR/8 HA; 533–541. The derivation of the CTL clone-4 TCR transgenic line (CL4) has been … dwts past winners listWebAug 28, 2007 · CL4-TCR T cells were purified by negative selection according to the manufacturer's instructions. Isolated CD8 + T cells were washed once in PBS and resuspended (4 × 10 7 cells/ml of PBS). Then … crystal mark discWebCL4-TCR transgenes by polymerase chain reaction (PCR) using specific primers. Mice were bred and maintained under specific pathogen-free conditions and used for experiments at 6 to 18 weeks of age. All animal experi-ments were performed in agreement with local regula-tions. crystalmark disk health